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US 2011/0212098 A1Published application
Novel Melanoma Antigen Peptide and Uses Thereof
AssigneesUniversite De Nantes, Chu Nantes, Inserm (Institut National De La Sante Et De La Recherche Medicale)
InventorsNathalie Labarriere, Agnes Moreau-Aubry, Yann Godet
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Abstract
The present invention relates to novel melanoma antigen peptides and specific T lymphocytes directed to said peptides and the use thereof for treating melanoma.
Claims15
A melanoma antigen peptide comprising the amino acids motif:
- TX2NDECWPX9
- (SEQ ID NO:
- 2)
- wherein X2 is leucine, methionine, valine, isoleucine or glutamine and X9 is alanine, valine or leucine,
- or
- RX2PPKPPLX9
- (SEQ ID NO:
- 3)
- wherein X2 is cysteine, leucine, methionine, valine, isoleucine or glutamine and X9 is alanine, valine or leucine.
6 more elements
An in vitro method for diagnosing a melanoma in a subject in need thereof, comprising detecting the expression of at least one of:
- MELOE mRNA (SEQ ID NO:
- 1),
- MELOE-1 polypeptide (SEQ ID NO:
- 4),
- MELOE-2 polypeptide (SEQ ID NO:
- 5),
- in a sample obtained from said subject.
4 more elements
Dependencies are inferred from the claim text.