Combination therapy for the treatment of liver diseases
AssigneeConatus Pharmaceuticals, Inc.
InventorAlfred P. Spada
Life of this patent
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Abstract
Provided herein are methods for treatment of a liver disease by administering a combination of a matrix metalloproteinase inhibitor and a caspase inhibitor. Also provided are methods for reducing liver damage associated with a liver disease by administering the MMP and caspase inhibitors described herein. Further provided are methods for lowering an elevated level of liver enzymes.
Claims25
A method for treating chronic hepatitis C comprising administering therapeutically effective amounts of
- and a caspase inhibitor to a patient in need thereof.
2-6. (canceled)
9-11. (canceled)
14-16. (canceled)
18-27. (canceled)
A method for lowering an elevated level of a liver enzyme comprising administering therapeutically effective amounts of
- and a caspase inhibitor to a patient in need thereof.
(canceled)
A method for reducing a liver damage associated with a chronic hepatitis C comprising administering therapeutically effective amounts of
- and a caspase inhibitor to a patient in need thereof.
(canceled)
A method for inhibiting Hepatitis C virus replication in a cell infected with Hepatitis C virus comprising contacting the cell with therapeutically effective amounts of
- and a caspase inhibitor.
A method for inhibiting HCV replication in a patient infected with Hepatitis C virus comprising administering therapeutically effective amounts of
- and a caspase inhibitor to the patient.
39-43. (canceled)
46-47. (canceled)
Dependencies are inferred from the claim text.