Hydrophobic deaeration membrane
AssigneeGambro Lundia AB
InventorChristof Beck
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Abstract
An optimized deaeration membrane has a biocompatible coating composition. Methods for preparing the membrane and the use of the membrane in medical devices for separating air from liquid that are administered to a living subject, e. g., blood processing devices used in dialysis and the like, are also described.
Claims20
A deaeration membrane comprising porous polytetrafluoroethylene in sheet form coated with a defoaming agent comprising a polysiloxane and silicon dioxide particles, wherein the amount of coating is from 4 μg per mm2 to 15 μg per mm2 of the membrane and the silicon dioxide particles are present in an average concentration of from 22,000 particles per mm2 to 44,000 particles per mm2 of the coated deaeration membrane.
A method for producing a deaeration membrane comprising porous polytetrafluoroethylene in sheet form coated with a defoaming agent comprising a polysiloxane and silicon dioxide particles, wherein the amount of coating is from 4 μg per mm2 to 15 μg per mm2 of the membrane and the silicon dioxide particles are present in an average concentration of from 22,000 particles per mm2 to 44,000 particles per mm2 of the coated deaeration membrane, the method comprising spray-coating a sheet of porous polytetrafluoroethylene with a solution comprising 0.1 wt. % to 20 wt. % of a defoaming agent comprising a polysiloxane and silicon dioxide particles.
A method for producing the a deaeration membrane comprising porous polytetrafluoroethylene in sheet form coated with a defoaming agent comprising a polysiloxane and silicon dioxide particles, wherein the amount of coating is from 4 μg per mm2 to 15 μg per mm2 of the membrane and the silicon dioxide particles are present in an average concentration of from 22,000 particles per mm2 to 44,000 particles per mm2 of the coated deaeration membrane, the method comprising roll coating a sheet of porous polytetrafluoroethylene with a solution comprising 20 wt. % to 70 wt. % of a defoaming agent comprising a polysiloxane and silicon dioxide particles.
A method for removing entrained gases from a liquid comprising passing the liquid containing the entrained gases through a deaeration membrane comprising porous polytetrafluoroethylene in sheet form coated with a defoaming agent comprising a polysiloxane and silicon dioxide particles, wherein the amount of coating is from 4 μg per mm2 to 15 μg per mm2 of the membrane and the silicon dioxide particles are present in an average concentration of from 22,000 particles per mm2 to 44,000 particles per mm2 of the coated deaeration membrane.
Dependencies are inferred from the claim text.