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US 2011/0086880 A1Published application
Novel alkyl substituted piperidine derivatives and their use as monoamine neurotransmitter re-uptake inhibitors
OwnerDan PETERS, Gunnar M. Olsen +3inventors
InventorsDan PETERS, Gunnar M. Olsen, Elsebet Østergaard Nielsen, Jørgen Scheel-Krüger, Birgitte L. Eriksen
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Abstract
This invention relates to novel alkyl substituted piperidine derivatives useful as monoamine neurotransmitter re-uptake inhibitors. In other aspects the invention relates to the use of these compounds in a method for therapy and to pharmaceutical compositions comprising the compounds of the invention.
Claims3
A piperidine derivative of the Formula I:
- any of its stereoisomers or any mixture of its stereoisomers, or a pharmaceutically acceptable salt thereof, wherein
- Ra represents hydrogen;
- X represents —NRc—;
- wherein Rc represents hydrogen or alkyl;
- Rb represents a naphthyl group,
- which naphthyl group is optionally substituted with one or more substituents independently selected from the group consisting of halo, trifluoromethyl, trifluoromethoxy, cyano, and alkoxy;
- each of R2, R2′, R6 and R6′ represent alkyl;
- and
- each of R3, R3′, R5 and R5′ represent hydrogen.
6 more elements
Dependencies are inferred from the claim text.