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US 2011/0086820 A1Published application
Analgesic agent comprising cyclic phosphatidic acid derivative
AssigneeOchanomizu University
InventorsKimiko MUROFUSHI, Harumi KANASHIKI
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Abstract
An object of the present invention is to elucidate an analgesic effect as one of new cPA bioactivities and thus to provide a novel analgesic agent. The present invention provides an analgesic agent which comprises a cyclic phosphatidic acid derivative that is one type of phospholipid.
Claims4
A method of alleviating pain comprising administering an effective amount to a patient in need thereof, a compound represented by the formula (1):
- wherein R presents C1-C30 linear or branched alkyl, C2-C30 linear or branched alkenyl, or C2-C30 linear or branched alkynl, provided that such groups are optionally substituted by a cycloalkane ring or an aromatic ring;
- X and Y each independently represents —O— or —C2—, provided that X and Y do not simultaneously represent —CH2—;
- and M represents a hydrogen atom or a counter cation, or a pharmacologically acceptable salt thereof, to alleviate pain.
Dependencies are inferred from the claim text.