Delivery agent
AssigneeFermentas UAB
InventorsArunas Lagunavicius, Lolita Zaliauskiene
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Abstract
A composition and method for delivering a peptide or protein into a cell.
Claims30
A composition for delivering a peptide or protein into a cell, the composition comprising a polycationic agent and a polyanionic agent, wherein the polyanionic agent comprises an inorganic polyphosphate or a polyoxometalate.
A kit for delivering a peptide or protein into a cell, the kit comprising a polycationic agent in a first container and a polyanionic agent in a second container, wherein the polyanionic agent comprises an inorganic polyphosphate or a polyoxometalate.
15-33. (canceled)
A method for delivering a peptide or protein into a target cell, the method comprising
- contacting the peptide or protein with a polycationic agent and a polyanionic agent to form a complex, and
- contacting the complex with the target cell to deliver the peptide or protein thereto, wherein:
- (1) the polyanionic agent comprises a polyphosphate or a polyoxometalate;
- and/or
- (2) the polycationic agent comprises a polyalkyleneimine.
(canceled)
A pharmaceutical product comprising a peptide or protein, a polycationic agent, and a polyanionic agent as a combined preparation, wherein;
- (1) the polyanionic agent comprises a polyphosphate or a polyoxometalate;
- and/or
- (2) the polycationic agent comprises a polyalkyleneimine.
Dependencies are inferred from the claim text.