Methods to inhibit cell growth
OwnerArthur B. RAITANO, Pia M. CHALLITA-EID +4inventors
InventorsArthur B. RAITANO, Pia M. CHALLITA-EID, Wangmao GE, Juan J. PEREZ-VILLAR, Steven B. KANNER, Aya JAKOBOVITS
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Abstract
A novel gene 109P1D4 and its encoded protein, and variants thereof, are described wherein 109P1D4 exhibits tissue specific expression in normal adult tissue, and is aberrantly expressed in the cancers listed in Table I. Consequently, 109P1D4 provides a diagnostic, prognostic, prophylactic and/or therapeutic target for cancer. The 109P1D4 gene or fragment thereof, or its encoded protein, or variants thereof, or a fragment thereof, can be used to elicit a humoral or cellular immune response; antibodies or T cells reactive with 109P1D4 can be used in active or passive immunization.
Claims20
A method for detecting a protein or polypeptide in a test sample, comprising:
- contacting the test sample with an antibody or fragment thereof that specifically binds to SEQ ID NO:
- 3 or a polynucleotide that specifically binds to SEQ ID NO:
- 2;
- and
- detecting binding of the antibody or fragment thereof or polynucleotide to a protein or polynucleotide, respectively, in the test sample.
A method for detecting a protein in a test sample, comprising:
- contacting the test sample with an antibody or fragment thereof that specifically binds to SEQ ID NO:
- 3;
- and
- detecting binding of the antibody or fragment thereof to a protein in the test sample.
Dependencies are inferred from the claim text.