Methods and devices for detecting ozone and carbonyl-containing compounds

A method of detecting the presence of ozone and carbonyl-containing compounds in an air sample, the method comprising:

• (a) drawing the air sample into a device;
• (b) contacting the air sample to a first bed comprising 1,2-bis(4-pyridyl)ethylene-coated silica particles, wherein ozone present in the air sample is trapped by reacting with the 1,2-bis(4-pyridyl)ethylene to form pyridine-4-aldehyde;
• (c) contacting the air sample to a second bed comprising 2,4-dinitrophenylhydrazine-coated silica particles, wherein a carbonyl-containing compound present in the air sample is trapped by reacting with the 2,4-dinitrophenylhydrazine to form carbonyl-2,4-dinitrophenylhydrazone;
• (d) eluting with a solvent from the second bed to the first bed, wherein excess 2,4-dinitrophenylhydrazine reacts with pyridine-4-aldehyde to form pyridine-4-aldehyde-2,4-dinitrophenylhydrazone;
• and
• (e) analyzing the carbonyl-2,4-dinitrophenylhydrazone and pyridine-4-aldehyde-2,4-dinitrophenylhydrazone formed in steps (c) and (d).

A device for detecting the presence of ozone and carbonyl-containing compounds in an air sample, the device comprising:

• a housing;
• means for drawing an air sample through the housing, wherein the air sample enters the housing through a first opening and exits the housing through a second opening;
• an ozone-reactive adsorbent disposed within the housing;
• and
• a carbonyl-reactive adsorbent disposed within the housing;
• wherein the ozone-reactive adsorbent and the carbonyl-reactive adsorbent are arranged within the housing such that at least a portion of the air sample drawn through the housing contacts the ozone-reactive adsorbent before the carbonyl-reactive adsorbent.

A device for detecting the presence of ozone and carbonyl-containing compounds in an air sample, the device comprising means for affecting a first mode of action and means for affecting a second mode of action, wherein the first mode and second mode co-act to detect the presence of ozone and carbonyl-containing compounds in the air sample;

• wherein the first mode of action comprises:
• (a) contacting an air sample with an ozone-reactive adsorbent wherein if ozone is present in the air sample, the ozone reacts with the ozone-reactive adsorbent to form an aldehyde product;
• and
• (b) contacting the air sample from Step (a) further with a carbonyl-reactive adsorbent wherein if a carbonyl-containing compound is present in the air sample, the carbonyl-containing compound reacts with the carbonyl-reactive adsorbent to form a first hydrazone product;
• and wherein the second mode of action comprises:
• (c) eluting with a solvent from the carbonyl-reactive adsorbent into the ozone-reactive adsorbent, wherein any aldehyde product of Step (a) forms a second hydrazone product;
• and
• (d) analyzing eluate from Step (c) for presence of hydrazone products formed in Step (b) and Step (c).

A kit for detecting the presence of ozone and carbonyl-containing compounds in an air sample comprising:

• (a) a cartridge;
• (b) an ozone-reactive adsorbent containing an ozone-reactive compound;
• (c) a carbonyl-reactive adsorbent containing a carbonyl-reactive compound;
• wherein the carbonyl-reactive compound differs from the ozone-reactive compound;
• and
• (d) a solvent for eluting derivatives of the ozone and carbonyl-containing compounds from the cartridge.

A device for detecting the presence of ozone and carbonyl-containing compounds in an air sample, the device comprising:

• a first housing and a second housing;
• means for drawing an air sample through the first and second housings;
• an ozone-reactive adsorbent disposed within the first housing;
• and
• a carbonyl-reactive adsorbent disposed within the second housing;
• wherein the air sample is drawn through the first housing and then through the second housing such that at least a portion of the air sample drawn through the first and second housings contacts the ozone-reactive adsorbent before the carbonyl-reactive adsorbent.

A device for detecting the presence of ozone and carbonyl-containing compounds in an air sample, the device comprising:

• an ozone-reactive adsorbent containing an ozone-reactive compound;
• a carbonyl-reactive adsorbent containing a carbonyl-reactive compound;
• wherein the carbonyl-reactive compound differs from the ozone-reactive compound;
• means for drawing an air sample through the ozone-reactive adsorbent and carbonyl-reactive adsorbent.