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US 2011/0086005 A1Published application
Modulating interstitial pressure and oncolytic viral delivery and distribution
AssigneeOncolytics Biotech Inc.
InventorsMatthew C. Coffey, Bradley G. Thompson, Hardev Pandha
Life of this patent
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Abstract
Provided herein are methods of treating a proliferative disorder in a subject comprising decreasing interstitial pressure and/or increasing vascular permeability in the subject and administering to the subject an oncolytic virus. Such methods improve oncolytic viral delivery and distribution.
Claims43
A method for treating a proliferative disorder in a subject, comprising the steps of:
- (a) decreasing interstitial pressure in the subject;
- and
- (b) administering to the subject one or more oncolytic viruses.
Dependencies are inferred from the claim text.