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US 2011/0085972 A1Published application
Nanotubes for cancer therapy and diagnostics
OwnerDan A. Buzatu, Jon G. Wilkes +5inventors
InventorsDan A. Buzatu, Jon G. Wilkes, Dwight Miller, Jerry A. Darsey, Tom Heinze, Alex Birts, Richard Beger
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Abstract
The present invention provides a novel approach to cancer therapy and diagnostics that utilizes nanotubes and other similar nanostructures as both an indirect source of radiation therapy (BNCT), and as delivery vehicles for other types of radio- and chemo-therapeutic materials, as well as imaging agents for diagnostic purposes.
Claims6
1-16. (canceled)
A method comprising:
- a) attaching a first IgG species to BN nanotubes to form BN nanotube-IgG composite species;
- b) administering said BN nanotube-IgG composite species to a mammalian subject such that the BN nanotube-IgG composite species targets tumors within said subject;
- and
- c) activating at least some of the boron atoms in the BN nanotube-IgG composite species;
- d) attaching radioactive isotopes to carbon nanotubes to form radioactive-laden carbon nanotubes;
- e) attaching a second IgG species to said radioactive-laden carbon nanotubes to form radioactive-laden carbon nanotube-IgG species;
- and
- f) introducing said radioactive-laden carbon nanotube-IgG species into the mammal;
- wherein the activating step comprises irradiating the subject with transdermal neutrons to activate the boron atoms.
6 more elements
Dependencies are inferred from the claim text.