Silicone Hydrogel Contact Lenses and Methods of Making Silicone Hydrogel Contact Lenses

A method of manufacturing a silicone hydrogel contact lens, comprising

• forming a silicone hydrogel contact lens body having an anterior surface and a posterior surface, wherein after hydration in water or an aqueous solution, at least one of the anterior surface and the posterior surface of the lens body when wet comprises a plurality of depressions with at least one of an average diameter between about 150 nanometers and less than 1500 nanometers and an average density from about 100 depressions per 900 μm2 to about 1200 depressions per 900 μm2, and wherein the lens body has not been subjected to a form of plasma treatment, the lens body has not been treated with a polymerizable swelling agent after the lens body is formed, or both.

A silicone hydrogel contact lens, comprising:

• a silicone hydrogel lens body comprising an anterior surface and a posterior surface, wherein, after hydration in water or an aqueous solution, at least one of the anterior surface and the posterior surface of the lens body when wet comprises a plurality of depressions with an average diameter between about 150 nanometers and less than 1500 nanometers, and wherein the lens body has not been subjected to a form of plasma treatment, the lens body has not been treated with a polymerizable swelling agent after the lens body is formed, or both.

A silicone hydrogel contact lens, comprising:

• a non-plasma treated silicone hydrogel lens body comprising an anterior surface and a posterior surface, at least one of the surfaces comprising a plurality of depressions having an average density from about 100 depressions per 900 μm2 to about 1200 depressions per 900 μm2.