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US 2011/0082220 A1Published application
Porcine umami taste receptors and uses therefor
AssigneesThe Regents of the University of California, Lucta
InventorsKirk Klasing, Roseline Holt, Eugeni Roura
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Abstract
The present invention provides nucleic acids encoding porcine taste receptors, polypeptides encoded by the nucleic acids, and methods of using the nucleic acids and polypeptides to identify compounds that enhance umami taste.
Claims14
A method of identifying a compound that modulates signal transduction of a porcine taste receptor in taste cells, the method comprising the steps of
- (i) contacting the compound with a porcine taste receptor comprising:
- a pT1R1 polypeptide having at least 90% sequence identity to SEQ ID NO:1;
- and a pT1R3 polypeptide having at least 90% sequence identity to SEQ ID NO:2;
- and
- (ii) determining a physical or functional effect of the compound upon the receptor, thereby identifying a compound that modulates porcine taste receptor signal transduction.
2 more elements
Dependencies are inferred from the claim text.