Nucleic acid and amino acid sequences relating to Staphylococcus epidermidis for diagnostics and therapeutics
AssigneeWyeth
InventorsLynn A. Doucette-Stamm, David Bush
Life of this patent
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Abstract
The invention provides isolated polypeptide and nucleic acid sequences derived from Staphylococcus epidermidis that are useful in diagnosis and therapy of pathological conditions; antibodies against the polypeptides; and methods for the production of the polypeptides. The invention also provides methods for the detection, prevention and treatment of pathological conditions resulting from bacterial infection.
Claims17
An isolated nucleic acid comprising the nucleotide sequence encoding the Staphylococcus epidermidis polypeptide set forth in SEQ ID NO:
- 5314.
(canceled)
An isolated nucleic acid comprising the nucleotide sequence encoding a Staphylococcus epidermidis polypeptide, wherein said nucleic acid consists of the nucleotide sequence set forth in SEQ ID NO:
- 2477.
(canceled)
(canceled)
(canceled)
11-28. (canceled)
An isolated nucleic acid which has at least 90% homology to the nucleotide sequence set forth in SEQ ID NO:
- 2477.
An isolated nucleic acid, wherein the nucleic acid is DNA, RNA, single-stranded antisense, or an RNA/DNA duplex comprising the nucleic acid sequence set forth SEQ ID NO:
- 2477, a transcription product of the nucleic acid sequence set forth in SEQ ID NO:
- 2477, or an antisense strand of the nucleic acid sequence set forth in SEQ ID NO:
- 2477.
An isolated nucleic acid which has at least 90% homology to the nucleotide sequence that encodes the polypeptide set forth in of SEQ ID NO:
- 5314.
Dependencies are inferred from the claim text.