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OwnerLane Bernard Scheiber, II, Lane Bernard Scheiberinventors
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Diabetes mellitus is a disease of elevated blood glucose, often directly related to a deficiency in insulin production or insulin receptor production. The innovative strategy of treatment described here utilizes modified viruses and virus-like vehicles to act as a transport mechanism to deliver modified messenger RNA molecules to target cells in the body. Delivering to the Beta cells in the body the modified messenger RNA needed to construction of insulin or insulin receptors will lead to enhanced production of biologically active insulin or insulin receptors by Beta cells as necessary, which will lead to correcting deficiencies in insulin or insulin receptors the result of which will help properly regulate blood glucose levels throughout the body utilizing innate regulatory mechanisms.
A medical treatment device consisting of a modified form of a virus that contains a quantity of medically therapeutic modified messenger ribonucleic acid molecules,
A medical treatment device consisting of a modified form of a virus carrying on its surface a quantity of probes that target cell-surface receptors on certain biologically active cells, said modified form of virus containing a quantity of modified messenger ribonucleic acid molecules for the purpose of inserting into said biologically active cell said quantity of said modified messenger ribonucleic acid molecules, said modified messenger ribonucleic acid molecules capable of engaging ribosomes to produce a specific protein inside said metabolically active cell for the purpose of carrying out a therapeutic medical treatment.
A medical treatment device consisting of a modified Hepatitis C virus, said Hepatitis C virus modified to have a quantity of surface probes to recognize, then engage one or more exterior cell-surface receptors on the surface of a Beta cell located in the Islets of Langerhans in the pancreas, said medical device expressing said quantity of surface probes intended to facilitate inserting said modified Hepatitis C virus's genome that it carries into said Beta cell, said Hepatitis C virus further modified to have its own innate positive sense ribonucleic acid genome replaced by a quantity of modified messenger ribonucleic acid molecules for the purpose of carrying out a medically therapeutic treatment.
A medical treatment device consisting of a virus-like transport vehicle comprised of a spherical shell of bilayer lipid material, embedded in said bilayer lipid surface of said virus-like transport vehicle a quantity of probes intended to target cell-surface receptors on specific biologically active cells, said virus-like transport vehicle containing a quantity of nested protein shells, said virus-like transport vehicle carrying inside said bilayer lipid shell a quantity of modified messenger ribonucleic acid molecules for the purpose of inserting into said biologically active cell said quantity of said modified messenger ribonucleic acid molecules, said modified ribonucleic acid molecules capable of engaging ribosomes to produce a specific protein inside said metabolically active cell for the purpose of carrying out a therapeutic medical treatment.
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