Gene therapy for diabetic ischemic disease
AssigneeAnGes MG, Inc.
InventorsRyuichi Morishita, Toshio Ogihara
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Abstract
It is possible to stimulate the angiogenesis of an ischemic site declined by diabetes and to recuperate ischemic disease by administering HGF (hepatocyte growth factor) gene to the diabetic ischemic.
Claims6
A method for the treatment of diabetic lower limb ischemic disease in a subject, comprising administering a therapeutically effective amount of a hepatocyte growth factor (HGF) gene to the muscle of an ischemic site, wherein expression of the HGF gene increases blood flow when compared to an HGF-treated non-diabetic subject with ischemic disease, thereby treating the diabetic lower limb ischemic disease.
Dependencies are inferred from the claim text.