US 2011/0035176 A1Published application

Apparatus for automatically testing integrated cmos magnetoresistive biochips

AssigneeDongguan Bosh Biotechnologies, Ltd.

InventorYunhua Gao

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Abstract

An apparatus for automatically testing CMOS magnetoresistive biochips is disclosed. The apparatus includes: means for directly or indirectly applying physical pressure to the fluid pumping chamber in a cartridge; a liquid injector for injecting liquid into the reaction chamber in the cartridge through an inlet or inlets in fluid connection to said reaction chamber; a CMOS magnetoresistive biochip located in the reaction chamber in the cartridge; means for applying a magnetic field to said CMOS magnetoresistive biochip in the cartridge; an electronic module for communicating with and supplying power as well as control signals to said biochip; a microprocessor to control and coordinate the aforementioned components; and a user interface for information processing. The apparatus provided by the present invention reduces the complexity of operation and enhances the detection sensitivity to a great extent.

Claims18

Dependent claims

An apparatus for automatically testing integrated CMOS magnetoresistive biochip comprising:

means for applying pressure directly or indirectly to a cartridge;
a liquid injection system connected to the cartridge for injecting liquid into the microfluidic channel or channels in said cartridge,
means for generating a magnetic field, by providing, according to requirements, a positive or negative current with certain intensity to a electromagnet to generate a positive or negative magnetic field with certain intensity, and for applying the positive or negative magnetic field to said integrated CMOS magnetoresistive biochip on said cartridge;
an electronic module for controlling and reading information from said biochip, to supply power and control signal to said integrated CMOS magnetoresistive biochip in said cartridge, communicate with a large scale integrated CMOS circuit on the biochip, test the information stored in the sensing elements of the integrated CMOS magnetoresistive biochip, and convert the tested analog signal to digital signal;
a microprocessor to control and coordinate the operation of the following components:
said means for applying pressure, said liquid injection system, said means for generating a magnetic field, and said electronic module for controlling and reading information from the biochip, and to process information measured under different magnetic fields;
a user interface connected to the microprocessor to receive and display information from said microprocessor.

4 more elements

An apparatus for automatically testing integrated CMOS magnetoresistive biochip comprising:

means for applying pressure directly or indirectly to a cartridge;
means for generating a magnetic field, by providing, according to requirements, a positive or negative current with certain intensity to a electromagnet to generate a positive or negative magnetic field with certain intensity, and for applying the positive or negative magnetic field to said integrated CMOS magnetoresistive biochip on said cartridge;
an electronic module for controlling and reading information from said biochip to supply power and control signal to said integrated CMOS magnetoresistive biochip in said cartridge, communicate with a large scale integrated CMOS circuit on the biochip, test the information stored in the sensing elements of the integrated CMOS magnetoresistive biochip, and convert the tested analog signal to digital signal;
a microprocessor to control and coordinate the operation of the following components:
said means for applying pressure, said liquid injection system, said means for generating a magnetic field, and said electronic module for controlling and reading information from the biochip, and to process information measured under different magnetic fields;
a user interface connected to the microprocessor to receive and display information from said microprocessor.

3 more elements

An apparatus for automatically testing integrated CMOS magnetoresistive biochips comprising:

a liquid injection system connected to the cartridge for injecting liquid into the microfluidic channel or channels in said cartridge,
means for generating a magnetic field, by providing, according to requirements, a positive or negative current with certain intensity to a electromagnet to generate a positive or negative magnetic field with certain intensity, and for applying the positive or negative magnetic field to said integrated CMOS magnetoresistive biochip on said cartridge;
an electronic module for controlling and reading information from said biochip, to supply power and control signal to said integrated CMOS magnetoresistive biochip in said cartridge, communicate with a large scale integrated CMOS circuit on the biochip, test the information stored in the sensing elements of the integrated CMOS magnetoresistive biochip, and convert the tested analog signal to digital signal;
a microprocessor to control and coordinate the operation of the following components:
said means for applying pressure, said liquid injection system, said means for generating a magnetic field, and said electronic module for controlling and reading information from the biochip, and to process information measured under different magnetic fields;
a user interface connected to the microprocessor to receive and display information from said microprocessor.

3 more elements

Dependencies are inferred from the claim text.