Correcting biological signal measurements from parallel measurement devices

A computer-implemented method for correcting data sets from measurements of properties of biological samples made with several different versions of a parallel measurement device, wherein the several different versions originate from one or more manufacturers and differ from one another in respect of at least one of hardware, software or measurement protocol;

• the method comprising:
• obtaining data sets wherein each data set contains property values of several properties of a biological sample, wherein the property values of the data set are based on measurements made with one of the several different versions of the parallel measurement device;
• storing the obtained data sets, wherein the storing comprises associating each data set with an indication of the version of the parallel measurement device on which the data set is based;
• determining at least one first property-specific distribution parameter and at least one second property-specific distribution parameter for each property, wherein the at least one first property-specific distribution parameter is determined for each version i of the parallel measurement device and the at least one second property-specific distribution parameter is determined for a combination of one or more of the versions of the parallel measurement device, wherein said combination of the one or more the versions comprises at least one version other than version i;
• determining a property-specific correction element for each version of the parallel measurement device based on the discrepancy between the at least one first property-specific distribution parameter and the at least one second property-specific distribution parameter;
• correcting a property's property value with the property-specific correction element for the version of the parallel measurement device on which the property's property value is based, thereby producing the property's corrected property value;
• and
• outputting the property's corrected property value to a physical memory and/or display.

A computer system for correcting data sets from measurements of properties of biological samples made with several different versions of a parallel measurement device, wherein the several different versions originate from one or more manufacturers and differ from one another in respect of at least one of hardware, software or measurement protocol;

• the computer system comprising:
• input means for obtaining data sets wherein each data set contains property values of several properties of a biological sample, wherein the property values of the data set are based on measurements made with one of the several different versions of the parallel measurement device;
• a database for storing the obtained data sets and for associating each data set with an indication of the version of the parallel measurement device on which the data set is based;
• first program means for determining at least one first property-specific distribution parameter and at least one second property-specific distribution parameter for each property, wherein the program means are operable to determine the at least one first property-specific distribution parameter for each version i of the parallel measurement device and the at least one second property-specific distribution parameter for a combination of one or more of the versions of the parallel measurement device, wherein said combination of the one or more the versions comprises at least one version other than version i;
• second program means for determining a property-specific correction element for each version of the parallel measurement device based on the discrepancy between the at least one first property-specific distribution parameter and the at least one second property-specific distribution parameter;
• third program means for correcting a property's property value with the property-specific correction element for the version of the parallel measurement device on which the property's property value is based, thereby producing the property's corrected property value;
• and
• output means for outputting the property's corrected property value to a physical memory and/or display.