Stents with drug-containing amphiphilic polymer coating

An intravascular stent comprising a metal body and a coating comprising a polymer and at least 20 μg per stent of a restenosis inhibiting agent in which the restenosis inhibiting agent is a sparingly water soluble drug and the polymer in the coating is a cross-linked amphiphilic polymer which, when swollen with water containing pyrene, has hydrophobic domains observable by pyrene fluorescence having an intensity ratio I3:I1 of at least 0.8,

• wherein the amphiphilic polymer comprises, as the groups conferring hydrophobicity, pendant hydrophobic groups selected from C4-24-alkenyl and -alkynyl groups any of which is optionally substituted by one or more fluorine atoms, aryl, C7-24 aralkyl, oligo (C3-4 alkoxy) alkyl and siloxane groups,
• as the groups conferring hydrophilicity, zwitterionic groups.