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US 2011/0034702 A1Published application
Method for preparing 4-[3,5-bis(2-hydroxyphenyl)-[1,2,4]triazol-1-yl]-benzoic acid
AssigneeFarmak, A S
InventorsRadek Melnicky, Pavel Hradil, Lubomir Kvapil, Martin Grepl, Petr Slezar
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Abstract
A method for preparing 4-[3,5-bis(2-hydroxyphenyl)-[1,2,4]triazol-1-yl]benzoic acid of formula (I) by reaction of 2-(2-hydroxyphenyl)benz[e][1,3]oxazin-4-one of formula (II) with 4-hydrazinobenzoic acid of formula (III) in an organic acid or in a mixture of an organic acid and an organic solvent.
Claims8
A method for preparing 4-[3,5-bis(2-hydroxyphenyl)-[1,2,4]triazol-1-yl]benzoic acid of formula I
- by reaction of 2-(2-hydroxyphenyl)benz[e][1,3]oxazin-4-one of formula II
- with 4-hydrazinobenzoic acid of formula III
- characterized in that the reaction is carried out in an organic acid or a mixture of an organic acid and an organic solvent.
Dependencies are inferred from the claim text.