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US 2011/0034674 A1Published application
Virus filtration methods
AssigneeGenentech, Inc.
InventorAmit Mehta
Life of this patent
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Abstract
The present invention relates to the field of protein purification. In particular, the invention concerns methods for increasing the filtration capacity of virus filters, by combined use of endotoxin removal and cation-exchange media in the prefiltration process.
Claims20
A method of improving the filtration capacity of a virus filter during protein purification, comprising subjecting a composition comprising a protein to be purified to a cation exchange step and an endotoxin removal step, simultaneously or in either order, prior to passing through said virus filter.
Dependencies are inferred from the claim text.