Inclusion Compounds of Fumagillol Derivative or its Salt, and Pharmaceutical Compositions Comprising the Same

An inclusion compound of fumagillol derivative of the Formula 1 or its salt with hydroxypropyl-β cyclodextrin or sulfobutylether-7-β cyclodextrin,

• wherein,
• X is hydroxy, Y is halogen, or X and Y together forms oxirane ring;
• B is O or H2;
• and R1, R2, R3, R4 and R5 independently represent hydrogen, hydroxy, acetoxy, C1-C6 alkyl, C1-C6 alkoxy, amino, alkylamino, dialkylamino, aminoalkyl, alkylaminoalkyl, dialkylaminoalkyl, aminoalkoxy, alkylaminoalkoxy, dialkylaminoalkoxy, halogen, cyano, trifluoromethyl, nitro, formyl, acetamido, methyleneoxycarboxy, methylenedioxy or ethylenedioxy group, provided that R1, R2, R3, R4 and R5 cannot be hydrogen at the same time.