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US 2011/0034487 A1Published application
Cxcr3 antagonists
AssigneeAmgen Inc.
InventorsXiaoqi Chen, Kirk Henne, Julio C. Medina
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Abstract
Compounds, compositions and methods that are useful in the treatment of inflammatory and immune conditions and diseases are provided herein. In particular, the invention provides compounds which modulate the expression and/or function of a chemokine receptor. The subject methods are useful for the treatment of inflammatory and immunoregulatory disorders and diseases, such as multiple sclerosis, rheumatoid arthritis, transplant rejection and type I diabetes.
Claims11
A compound having the formula (I):
- and salts thereof wherein R1 is chloro or fluoro.
Dependencies are inferred from the claim text.