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US 2011/0034416 A1Published application
4-pyridinone compounds and their use for cancer
AssigneeBristol-Myers Squibb Company
InventorsRobert M. Borzilleri, Zhen-Wei Cai
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Abstract
Disclosed are compounds of Formula (I): and salts thereof. Also, disclosed are methods of using the compounds in the treatment of proliferative diseases, such as cancer, and to pharmaceutical compositions comprising at least one compound of Formula (I) or a pharmaceutically acceptable salt.
Claims13
A compound having the following Formula (I):
- or a salt thereof, wherein:
- G is H, —CHX—OP(═O)(OH)2, or —CHX—OC(═O)Z;
- X is H or alkyl optionally substituted with one or more of OH, halogen, cyano, and/or —NR1R2;
- Z is alkyl, cycloalkyl, aryl, or heterocyclo optionally substituted with one or more of alkyl, OH, halogen, cyano, and/or —NR3R4;
- and
- R1, R2, R3, and R4 are independently H and/or alkyl.
3 more elements
Dependencies are inferred from the claim text.