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US 2011/0033954 A1Published application
Biofunctionalized quantum dots for biological imaging
AssigneeThe Government of the United State of America, as Represented by the Secretary, Department of Health
InventorsJoseph J. Barchi, JR., Serge A. Svarovsky
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Abstract
Novel biofunctionalized quantum dots include a mercaptoalkanoic acid linked to the surface of a nanocrystalline core and a biofunctional group linked to the surface. Biofunctionalized quantum dots are made by a novel synthesis method. Biofunctionalized quantum dots can be used in imaging or therapy applications.
Claims11
A biofunctionalized quantum dot, comprising:
- a nanocrystalline core exhibiting quantum confinement and having a band gap and a surface;
- a mercaptoalkanoic acid linked to the surface;
- and
- a biofunctional group linked to the surface,
- wherein the biofunctional group comprises a saccharide or the mercaptoalkanoic acid is linked to the surface of the nanocrystalline core without a shell layer.
2 more elements
Dependencies are inferred from the claim text.