Novel members of the capsaicin/vanilloid receptor family of proteins and uses thereof
AssigneeBayer Schering Pharma Aktiengesellschaft
InventorRory A. J. Curtis
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AssigneeBayer Schering Pharma Aktiengesellschaft
InventorRory A. J. Curtis
Estimating the term…
The invention provides isolated nucleic acids molecules, designated hVR-1, hVR-2, and rVR-2 nucleic acid molecules, which encode novel members of the Capsaicin/Vanilloid receptor family. The invention also provides antisense nucleic acid molecules, recombinant expression vectors containing hVR-1, hVR-2, and rVR-2 nucleic acid molecules, host cells into which the expression vectors have been introduced, and nonhuman transgenic animals in which an hVR-1, hVR-2, and rVR-2 gene has been introduced or disrupted. The invention still further provides isolated hVR-1, hVR-2, and rVR-2 proteins, fusion proteins, antigenic peptides and anti-hVR-1, anti-hVR-2, and anti-rVR-2 antibodies. Diagnostic methods utilizing compositions of the invention are also provided.
An isolated nucleic acid molecule selected from the group consisting of:
An isolated polypeptide selected from the group consisting of:
Dependencies are inferred from the claim text.