Luminescent substrate for liciferase
AssigneeThe University of Electro-Communications
InventorsShojiro Maki, Satoshi Kojima, Haruki Niwa
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Abstract
The present invention relates to a compound having a structure analogous to firefly luciferin. In particular, the invention relates to a heterocycle compound which produces a luminescence at a light wavelength different from that of firefly luciferin in nature. The present invention provides a heterocycle compound of following general formula I. In the above general formula, R1, R2 and R3 can be each independently H or C1-4-alky. In the above general formula, X and Y can be each independently C, N, S or O. In the above general formula, the olefin chain part expressed as “n” can be changed to desired length.
Claims6
A luminescent substrate consisting of a heterocycle compound of following general formula I or the salt thereof:
- Wherein,
- R1, R2 and R3 are each independently H or C1-4-alkyl,
- X and Y are each independently C, N, S or O and
- n is 0, 1, 2 or 3.
A heterocycle compound of following general formula I or the salt thereof:
- Wherein,
- wherein R1, R2 and R3 are each independently H or C1-4-alkyl,
- X and Y are each independently C, N, S or O and
- n is 0, 1, 2 or 3,
- providing that the compound wherein R1 and R2 are H, X is N, Y is S and n is 0, the compound wherein R1, R2 and R3 are methyl, X is N, Y is S and n is 1, the compound wherein R1 and R2 are H, R3 is ethyl, X is N, Y is C and n is 0, the compound wherein R1, R2 and R3 are H, X is N, Y is C and n is 0, and the compound wherein R1 and R2 are methyl, X is N, Y is S, and n is 1 are excluded.
(canceled)
Dependencies are inferred from the claim text.