Proteinic marker for early diagnosis of liver cancer

Proteomic markers for early detection of liver cancer comprising one or more of the following polypeptides:

• A1XP52_HUMAN (catecholamine-regulated protein 40;
• NCBI GI:94450030);
• ARSA1_HUMAN (arsA arsenite transporter, ATP-binding, homolog 1;
• NCBI GI:50428938);
• MAAI_HUMAN (glutathione transferase zeta 1;
• NCBI GI:3510757);
• UGDH_HUMAN (UDP-glucose dehydrogenase;
• NCBI GI:4507813);
• NDUS3_HUMAN (NADH dehydrogenase (ubiquinone) Fe-S protein 3, 30 kDa (NADH-coenzyme Q reductase);
• NCBI GI:4758788);
• FTHFD_HUMAN (formyltetrahydrofolate dehydrogenase isoform a variant;
• NCBI GI:3560541);
• ATP5H_HUMAN (ATP synthase, H+ transporting, mitochondrial F0 complex, subunit d isoform a;
• NCBI GI:5453559);
• ERLN2_HUMAN (ER lipid raft associated 2 isoform 1;
• NCBI GI:6005721);
• SNP29_HUMAN (synaptosomal-associated protein 29;
• NCBI GI:4759154);
• AIFM1_HUMAN (programmed cell death 8 isoform 2;
• NCBI GI:22202629);
• LDHA_HUMAN (lactate dehydrogenase A variant;
• NCBI GI:62897717);
• ADA_HUMAN (adenosine deaminase;
• NCBI GI:47078295);
• CO3_HUMAN (Chain B, Human Complement Component C3;
• NCBI GI:78101268);
• LMNA_HUMAN (lamin A/C isoform 2;
• NCBI GI:5031875);
• APOA1_HUMAN (apolipoprotein A-I, isoform CRA_b;
• NCBI GI:119587681);
• FRIH_HUMAN (FTH1 protein;
• NCBI GI:76779199);
• ANXA1_HUMAN (Chain A, Crystal Structure Of Human Annexin I At 2.5 Angstroms Resolution;
• NCBI GI:157829895);
• ARLY_HUMAN (argininosuccinate lyase;
• NCBI GI:18033920);
• APT_HUMAN (adenine phosphoribosyltransferase isoform a;
• NCBI GI:4502171);
• HSP71_HUMAN (heat shock 70 kDa protein 1B;
• NCBI GI:147744565);
• HS90B_HUMAN (90 kDa heat shock protein;
• NCBI GI:306891);
• ADH4_HUMAN (Alcohol dehydrogenase 4 (Alcohol dehydrogenase class II pi chain);
• NCBI GI:83286923);
• GSTA2_HUMAN (glutathione S-transferase A2 subunit;
• NCBI GI:257476);
• VILI_HUMAN (villin 1;
• NCBI GI:6005944);
• ODB2_HUMAN (branched chain acyltransferase precursor;
• NCBI GI:179354);
• PYC_HUMAN (pyruvate carboxylase precursor;
• NCBI GI:106049292);
• KU70_HUMAN (ATP-dependent DNA helicase II, 70 kDa subunit;
• NCBI GI:4503841);
• KU86_HUMAN (ATP-dependent DNA helicase II;
• NCBI GI:10863945);
• TCTP_HUMAN (tumor protein, translationally-controlled 1;
• NCBI GI:4507669);
• PLSL_HUMAN (L-plastin;
• NCBI GI:4504965);
• ACPH_HUMAN (N-acylaminoacyl-peptide hydrolase;
• NCBI GI:23510451);
• GLNA_HUMAN (GLUL protein;
• NCBI GI:22749655);
• AK1C4_HUMAN (Aldo-keto reductase family 1 member C4 (Chlordecone reductase) (CDR);
• NCBI GI:1705823);
• TCPA_HUMAN (T-complex protein 1 isoform a;
• NCBI GI:57863257);
• VINC_HUMAN (vinculin;
• NCBI GI:4507877);
• TYPH_HUMAN (endothelial cell growth factor 1 (platelet-derived);
• NCBI GI:4503445);
• IREB1_HUMAN (aconitase 1;
• NCBI GI:8659555);
• ODBB_HUMAN (chain B, human branched-chain alpha-keto acid dehydrogenase;
• NCBI GI:7546385);
• TGM2_HUMAN (transglutaminase 2 isoform a;
• NCBI GI:39777597);
• CPT2_HUMAN (carnitine palmitoyltransferase II;
• NCBI GI:4503023);
• EF1B_HUMAN (eukaryotic translation elongation factor 1 beta 2;
• NCBI GI:4503477);
• MOES_HUMAN (moesin;
• NCBI GI:4505257);
• EF1G_HUMAN (eukaryotic translation elongation factor 1 gamma, isoform CRA_d;
• NCBI GI:119594432);
• AOFB_HUMAN (monoamine oxidase B;
• NCBI GI:38202207);
• 1433T_HUMAN (tyrosine 3/tryptophan 5-monooxygenase activation protein, theta polypeptide;
• NCBI GI:5803227);
• PSB9_HUMAN (proteasome beta 9 subunit isoform 2 proprotein;
• NCBI GI:23110932);
• TKT_HUMAN (transketolase;
• NCBI GI:4507521);
• AL4A1_HUMAN (aldehyde dehydrogenase 4A1 precursor;
• NCBI GI:25777734);
• ERP29_HUMAN (endoplasmic reticulum protein 29 isoform 1 precursor;
• NCBI GI:5803013);
• 2AAA_HUMAN (Chain A, Structure Of A Complex Between The A Subunit Of Protein Phosphatase 2a And The Small T Antigen Of Sv40;
• NCBI GI:149243188);
• AL1B1_HUMAN (aldehyde dehydrogenase 1B1 precursor;
• NCBI GI:25777730);
• QCR1_HUMAN (ubiquinol-cytochrome c reductase core protein I;
• NCBI GI:46593007);
• HNRH1_HUMAN (heterogeneous nuclear ribonucleoprotein H1;
• NCBI GI:5031753);
• 1433B_HUMAN (tyrosine 3-monooxygenase/tryptophan 5-monooxygenaseactivation protein, beta polypeptide;
• NCBI GI:4507949);
• PRDX2_HUMAN (peroxiredoxin 2 isoform2;
• NCBI GI:32189392);
• ACSL1_HUMAN (acyl-CoA synthetase long-chain family member 1;
• NCBIGI:40807491);
• PHB_HUMAN (prohibitin;
• NCBI GI:4505773);
• CBS_HUMAN (cystathionine-beta-synthase;
• NCBI GI:4557415);
• MYH9_HUMAN (Nonmuscle myosin heavy chain A;
• NCBI GI:189030);
• ODO2_HUMAN (dihydrolipoamide succinyltransferase;
• NCBI GI:643589);
• PEX19_HUMAN (peroxisomal biogenesis factor 19;
• NCBI GI:4506339);
• LPPRC_HUMAN (leucine-rich PPR motif-containing protein;
• NCBIGI:31621305);
• CAZA2_HUMAN (capping protein alpha;
• NCBI GI:433308);
• UCRI_HUMAN (ubiquinol-cytochrome c reductase, Rieske iron-sulfurpolypeptide 1;
• NCBI GI:5174743);
• TCPE_HUMAN (chaperonin containing TCP1, subunit 5 (epsilon);
• NCBIGI:24307939);
• AL9A1_HUMAN (4-trimethylaminobutyraldehyde dehydrogenase (TMABADH) (Aldehyde dehydrogenase family 9 member A1) (Aldehyde dehydrogenase E3isozyme) (Gamma-aminobutyraldehyde dehydrogenase) (R-aminobutyraldehydedehydrogenase);
• NCBI GI:62511242);
• HINT1_HUMAN (histidine triad nucleotide binding protein 1;
• NCBI GI:4885413);
• ST1A1_HUMAN (phenol sulfotransferase;
• NCBI GI:847763);
• SSRD_HUMAN (signal sequence receptor, delta;
• NCBI GI:5454090);
• GDIR_HUMAN (Chain A, Structure Of Rho Guanine Nucleotide Dissociation Inhibitor;
• NCBI GI:2624719);
• KAD2_HUMAN (adenylate kinase 2 isoform b;
• NCBI GI:7524346);
• SNAA_HUMAN (N-ethylmaleimide-sensitive factor attachment protein, alpha;
• NCBI GI:47933379);
• TERA_HUMAN (Valosin-containing protein;
• NCBI GI:6005942);
• 1433E_HUMAN (tyrosine 3/tryptophan 5-monooxygenase activation protein, epsilon polypeptide;
• NCBI GI:5803225);
• 1433Z_HUMAN (tyrosine 3/tryptophan 5-monooxygenase activation protein, zeta polypeptide;
• NCBI GI:4507953);
• SKP1_HUMAN (S-phase kinase-associated protein 1 isoform b;
• NCBI GI:25777713);
• ACTG_HUMAN (ACTB protein;
• NCBI GI:15277503);
• HBB_HUMAN (beta globin;
• NCBI GI:4504349);
• TCPB_HUMAN (CCT2;
• NCBI GI:48146259);
• SET_HUMAN (SET translocation (myeloid leukemia-associated);
• NCBI GI:145843637);
• MMSA _HUMAN (aldehyde dehydrogenase 6A1 precursor;
• NCBI GI:11095441);
• BDH_HUMAN (3-hydroxybutyrate dehydrogenase precursor;
• NCBI GI:17738292);
• LGUL_HUMAN (glyoxalase I;
• NCBI GI:118402586);
• ST2A1_HUMAN (sulfotransferase family, cytosolic, 2Adehydroepiandrosterone-preferring, member 1;
• NCBI GI:29540545);
• C1QBP_HUMAN (tat-associated protein;
• NCBI GI:1096067);
• PRDX4_HUMAN (thioredoxin peroxidase;
• NCBI GI:5453549);
• FCL_HUMAN (tissue specific transplantation antigen P35B;
• NCBI GI:4507709);
• DPYS_HUMAN (dihydropyrimidinase;
• NCBI GI:4503375);
• GANAB_HUMAN (Glucosidase II;
• NCBI GI:2274968);
• MVP_HUMAN (major vault protein;
• NCBI GI:19913410);
• UGPA_HUMAN (UTP-glucose-1-phosphate uridylyltransferase;
• NCBI GI:2136353);
• IMMT_HUMAN (motor protein;
• NCBI GI:516766);
• GLE1_HUMAN (GLE1 RNA export mediator homolog isoform 2;
• NCBI GI:4557627);
• Q56G89_HUMAN (serum albumin;
• NCBI GI:62113341);
• TOIP 1_HUMAN (torsin A interacting protein 1, isoform CRA_b;
• NCBI GI:119611474);
• Q5U0A0_HUMAN (proteasome (prosome, macropain) subunit, alpha type, 5;
• NCBI GI:54696300);
• F108B_HUMAN (family with sequence similarity 108, member B1 isoform 2;
• NCBI GI:71051602);
• HIBCH_HUMAN (3-hydroxyisobutyryl-coenzyme A hydrolase;
• NCBI GI:3320120);
• DCXR_HUMAN (dicarbonyl/L-xylulose reductase;
• NCBI GI:7705925);
• PTOV1_HUMAN (prostate tumor overexpressed gene 1, isoform CRA_b;
• NCBI GI:7920398);
• GLCTK_HUMAN (CG9886-like;
• NCBI GI:31543063);
• CS010_HUMAN (R33729—1;
• NCBI GI:3355455);
• FAH2A_HUMAN (CGI-105 protein;
• NCBI GI:4929679);
• ABHEB_HUMAN (abhydrolase domain containing 14B;
• NCBI GI:14249382);
• CPNE1_HUMAN (copine I;
• NCBI GI:4503013);
• SPEB_HUMAN (agmatinase;
• NCBI GI:18031951);
• CK054_HUMAN (proteasome activator hPA28 suunit beta;
• NCBI GI:48257065);
• BHMT2_HUMAN (betaine-homocysteine methyltransferase 2;
• NCBI GI:13162290);
• MCCC2_HUMAN (methylcrotonoyl-Coenzyme A carboxylase 2 (beta);
• NCBI GI:11545863);
• DBLOH_HUMAN (DIABLO protein;
• NCBI GI:13325198);
• TMOD3_HUMAN (tropomodulin3;
• NCBI GI:6934244);
• VPS29_HUMAN (vacuolar protein sorting 29 isoform 1;
• NCBI GI:7706441);
• GRHPR_HUMAN (glyoxylate reductase/hydroxypyruvate reductase, isoform CRA_a;
• NCBI GI:119578687);
• PCYOX_HUMAN (prenylcysteine oxidase 1;
• NCBI GI:6561481);
• PSME2_HUMAN (proteasome activator hPA28 suunit beta;
• NCBI GI:1008915).