Nucleic acid microspheres, production and delivery thereof
AssigneesBaxter International Inc., Baxter Healthcare S.A.
InventorsTERRENCE SCOTT, DEBRA LAFRENIERE, VERED BISKER-LEIB, LARRY BROWN
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Abstract
Nucleic acids are prepared by dissolving compounds containing them in a suitable solvent or solvent system and forming microspheres from the resulting solution. The microspheres are administered to an individual as protection from conditions where delivery of nucleic acids is useful, such as in treatment of autoimmune disease.
Claims23
Microspheres comprising between about 20 weight percent and about 100 weight percent of one or more nucleic acids, and having an average particle size of not greater than about 50 microns, wherein the microspheres are substantially free of water soluble polymer used in microsphere preparation.
-36. (canceled)
Dependencies are inferred from the claim text.