Nanoparticle carriers for drug administration and process for producing same
AssigneeCsir
InventorLonji Kalombo
Life of this patent
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Abstract
The invention provides a process for the production of nanoparticle carriers for drug delivery, said nanoparticles being produced by preparing a double emulsion of water-oil-water including one or more polymer which forms the basis of the nanoparticle carrier, blending the drug to be delivered into one of the emulsion phases, doping either the oil-phase or the outer-water phase with a carbohydrate, and spray drying the emulsion to form nanoparticles of a narrow particle size distribution of 100 nm to 1000 nm, which nanoparticles are substantially spherical.
Claims23
A process for the production of nanoparticle carriers for drug delivery, said nanoparticles being produced by:
- preparing a double emulsion of water-oil-water including one or more polymer which forms the basis of the nanoparticle carrier;
- blending the drug to be delivered into one of the emulsion phases;
- doping either the oil-phase or the outer-water phase with a carbohydrate;
- doping either the oil-phase or the water phase with a surfactant;
- and
- spray drying the emulsion to form nanoparticles of a narrow particle size distribution of 100 nm to 1000 nm.
Dependencies are inferred from the claim text.