Methods and compositions for bone healing by periostin
AssigneeMedical University of South Carolina
InventorsRoger R. Markwald, Michael J. Kern, Russell A. Norris, Kyle P. Kokko
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Abstract
The present invention provides methods and compositions for increasing bone production and/or decreasing bone fracture healing time in a subject, by administering an effective amount of periostin and/or active peptides and/or fragments thereof.
Claims14
A method of increasing bone production in a subject, comprising administering to the subject an effective amount of a periostin protein or a biologically active fragment thereof and/or a periostin peptide, thereby increasing bone production in the subject.
A method of decreasing healing time of a bone fracture in a subject in need thereof, comprising administering to the subject an effective amount of a periostin protein or a biologically active fragment thereof and/or a periostin peptide, thereby decreasing healing time of a bone fracture in the subject.
Dependencies are inferred from the claim text.