Vaccines for brucellosis
OwnerDominic Charles Jenner, Helen Susan Atkinsinventors
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Abstract
A polypeptide selected from the group consisting of BMEII0923, BMEI0411, a protective fragment of BMEII0923 and BMEI0411 and immunologically active variants of BMEII0923 and BMEIO411, which provides a protective immune response against Brucella infection, for use as a vaccine against Brucellosis. Pharmaceutical compositions comprising these polypeptides and antibodies raised against these polypeptides are described and claimed. Such pharmaceutical compositions are useful in both active and passive vaccination against Brucella infections and may be used to treat Brucella infection or Brucellosis after exposure to the bacteria.
Claims15
A polypeptide selected from the group consisting of BME110923, BMEI0411, a protective fragment of BME110923, a protective fragment of BMEI0411, an immunologically active variant of BME110923, and an immunologically active variant of BMEI0411, wherein the polypeptide provides a protective immune response against Brucella infection when administered to a mammal.
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Dependencies are inferred from the claim text.