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US 2011/0033473 A1Published application
Anti influenza antibodies and uses thereof
OwnerYoram Reiter, Avital Levinventors
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Abstract
Provided are antibodies comprising an antigen recognition domain capable of binding an MHC molecule being complexed with an influenza peptide wherein the antibody does not bind the MHC molecule in an absence of the complexed peptide and wherein the antibody does not bind the peptide in an absence of the MHC molecule. Also provided are methods of using same for diagnosing and treating influenza.
Claims18
An isolated antibody comprising an antigen recognition domain capable of binding an MHC molecule being complexed with an influenza peptide derived from an influenza polypeptide selected from the group consisting of SEQ ID NOs:
- 19, 20, 21, 22, 23, 24, 25, 26, 27, 28, 29, 30, 31, 32, 33, 34 and 35, wherein the antibody does not bind said MHC molecule in an absence of said complexed peptide, and wherein the antibody does not bind said peptide in an absence of said MHC molecule.
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Dependencies are inferred from the claim text.