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US 2011/0033468 A1Published application
Ophthalmic Drug Delivery System Containing Phospholipid and Cholesterol
AssigneeTaiwan Liposome Co., Ltd.
InventorsSheue-Fang Shih, Po-Chun Chang, Yun-Long Tseng, Luke S.S. Guo, Keelung Hong
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Abstract
An ophthalmic drug delivery system that contains phospholipid and cholesterol for prolonging drug lifetime in the eyes.
Claims32
A drug delivery system, comprising
- a delivery vehicle containing phospholipid and cholesterol, and
- a therapeutic agent;
- wherein 50-90% of the therapeutic agent is in non-associated form and the weight ratio of the phospholipid and cholesterol in combination to the therapeutic agent is 5-80 to 1.
A method for delivering a therapeutic agent to an eye of a subject, comprising
- providing a composition containing a therapeutic agent and a delivery vehicle including phospholipid and cholesterol, and
- administering the composition to an eye of a subject in need;
- wherein 50-90% of the therapeutic agent is in non-associated form and the weight ratio of the phospholipid and cholesterol in combination to the therapeutic agent is 5-80 to 1.
Dependencies are inferred from the claim text.