Debridement Method Using Topical Nitric Oxide Donor Devices and Compositions
AssigneesThe University of Akron, KCI USA, Inc.
InventorsDaniel J. Smith, Patrick J. Trotter, Mahesh Bhide
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Abstract
The present invention relates to methods for removal of dead tissue from wounds or skin using topical nitric oxide donor devices and/or compositions. In one embodiment, the present invention relates to a transdermal patch device that is designed to deliver nitric oxide. In another embodiment, the present invention relates to one or more devices and/or compositions that are designed to deliver nitric oxide and optionally one or more other compounds, where such devices/compositions include, without limitation, bandages, layered bandages, adhesive bandages, transdermal patches, creams, ointments, or a any combination of two or more thereof.
Claims24
A method for facilitating the removal of necrotic skin comprising:
- applying a nitric oxide-forming composition or device to a wound;
- dosing wound tissue with an effective amount of nitric oxide, wherein the nitric oxide loosens necrotic wound tissue;
- and
- removing the loosened necrotic wound tissue.
Dependencies are inferred from the claim text.