Solubilized benzoyl small molecule
AssigneeTransdermal Corp
InventorPankaj Modi
Life of this patent
Estimating the term…
Abstract
The invention relates to a novel solubilized small molecule topical formulation for the transdermal delivery of small molecule agents comprising: a small molecule agent, one or more micelle forming compounds, one or more skin penetration enhancers, a surfactant, and one or more solvents, wherein the small molecule agent is solubilized in the solvent. The invention further relates to the use of the topical formulation as well as the process for making the topical formulation.
Claims41
A solubilized small molecule agent topical formulation comprising:
- small molecule agent;
- one or more micelle forming compounds;
- one or more solvents;
- one or more skin penetration enhancers;
- and
- a surfactant.
A process for the preparation of a solubilized small molecule agent topical formulation, said process comprising:
- a. Combining one or more micelle forming compounds, one or more penetration enhancers, one or more solvents and surfactant at 25 to 40° C. with constant stirring;
- b. Adding small molecule agent powder to the foregoing solution;
- and
- c. Cooling the resultant solution to room temperature.
A solubilized small molecule formulation comprising:
- a small molecule anti viral active agent;
- one or more micelle forming compounds
- one or more solvents;
- one or more skin penetration enhancers;
- and
- a surfactant.
A solubilized small molecule formulation comprising:
- a small molecule antibiotic active agent;
- one or more micelle forming compounds
- one or more solvents;
- one or more skin penetration enhancers;
- and
- a surfactant.
A solubilized small molecule formulation comprising:
- a small molecule antifungal active agent;
- one or more micelle forming compounds
- one or more solvents;
- one or more skin penetration enhancers;
- and
- a surfactant.
A solubilized small molecule formulation comprising:
- a small molecule corticosteroid active agent;
- one or more micelle forming compounds
- one or more solvents;
- one or more skin penetration enhancers;
- and
- a surfactant.
Dependencies are inferred from the claim text.