Method of determination of pdh activity and imaging media for use in said method
AssigneeGe Healthcare Limited
InventorsMarie A. Schroeder, Lowri E. Cochlin, Helen J. Atherton, Lisa C. Heather, Kieran Clarke, George K. Radda, Damian J. Tyler
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Abstract
The invention relates to a method of determination of PDH activity by 13C-MR detection using an imaging medium which comprises hyperpolarised 13C-pyruvate and to imaging media for use in said method.
Claims17
Method of determining pyruvate dehydrogenase (PDH) activity by 13C-MR detection using an imaging medium comprising hyperpolarised 13C-pyruvate wherein the signal of 13C-bicarbonate and optionally the signal of 13C-pyruvate are detected.
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MR imaging medium comprising malate and hyperpolarised 13C-pyruvate.
MR imaging medium comprising hyperpolarised 13C-pyruvate and hyperpolarised 13C-acetate.
Dependencies are inferred from the claim text.