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US 2011/0030808 A1Published application
Pulsed laser triggered high speed microfluidic switch and applications in fluorescent activated cell sorting
AssigneeThe Regents of the University of California
InventorsPei-Yu Chiou, Ting-Hsiang Wu
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Abstract
In certain embodiments this invention provides a pulsed-laser triggered microfluidic switching mechanism that can achieve a switching time of 70 μs. This switching speed is two orders of magnitude shorter than that of the fastest switching mechanism utilized in previous μFACS.
Claims24
A high-speed microfluidic switch, said switch comprising:
- a first microfluidic channel comprising a bifurcation into two or more paths, said two or more paths comprising at least a first path and a second path;
- and
- a chamber or second channel adjacent to said bifurcation disposed such that formation of a gas or plasma bubble in said chamber or adjacent channel redirects particles flowing into said first path so they flow into said second path.
A high-speed microfluidic switch, said switch comprising:
- a first microfluidic channel comprising a bifurcation into two or more paths, said two or more paths comprising at least a first path and a second path;
- a chamber or second microfluidic channel adjacent to said first microfluidic channel;
- a connecting port or channel connecting said chamber or microfluid channel to said first microfluidic channel;
- and
- a third channel or chamber adjacent to said chamber or second microfluidic channel disposed such that the formation of a bubble in said third channel or chamber induces a fluid flow or pressure through said connecting port or channel that redirects particles flowing into said first path so they flow into said second path.
2 more elements
Dependencies are inferred from the claim text.