Nucleic acid and amino acid sequences relating to staphylococcus epidermidis for diagnostics and therapeutics
AssigneeWyeth
InventorsLynn A. Doucette-Stamm, David Bush
Life of this patent
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Abstract
The invention provides isolated polypeptide and nucleic acid sequences derived from Staphylococcus epidermidis that are useful in diagnosis and therapy of pathological conditions; antibodies against the polypeptides; and methods for the production of the polypeptides. The invention also provides methods for the detection, prevention and treatment of pathological conditions resulting from bacterial infection.
Claims19
1-7. (canceled)
A method for producing a Staphylococcus epidermidis polypeptide comprising culturing a cell comprising a recombinant expression vector comprising a nucleic acid encoding SEQ ID NO:
- 5314 under conditions that permit expression of the polypeptide.
9-10. (canceled)
An immunogenic composition for prevention or treatment of a Staphylococcus epidermidis infection comprising an effective amount of an isolated polypeptide of claim 30.
A recombinant or substantially pure preparation of a Staphylococcus epidermidis polypeptide or a fragment thereof of SEQ ID NO:
- 5314.
24-28. (canceled)
An isolated polypeptide comprising SEQ ID NO:
- 5314.
An isolated polypeptide consisting of SEQ ID NO.:
- 5314.
Dependencies are inferred from the claim text.