Hybrid soft tissue implants from progenitor cells and biomaterials
AssigneeThe Trustees of Columbia University in the City of New York
InventorsJeremy J. Mao, Eduardo K. Moioli
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Abstract
Provided are hybrid soft tissue constructs comprising a core material, a biomaterial matrix and mammalian cells. Also provided are methods of augmenting or reconstructing a soft tissue of a mammal. Additionally, methods of forming a hybrid soft tissue construct are provided. The use of the above constructs for augmenting or reconstructing a soft tissue of a mammal are further provided. Additionally provided is the use of the above constructs for the manufacture of a medicament for augmenting or reconstructing a soft tissue of a mammal.
Claims21
1-57. (canceled)
A hybrid soft tissue construct comprising:
- a core material;
- a biomaterial matrix;
- and
- mammalian cells;
- wherein
- the core material is acellular and biocompatible;
- the biomaterial matrix comprises the mammalian cells;
- and
- the biomaterial matrix covers the acellular core.
Dependencies are inferred from the claim text.