Non-Biodegradable Stent Comprising a Biodegradable Coating and Method of Coating The Same
AssigneeNanyang Technological University
InventorsSubramanian Venkatraman, Yin Chiang Boey, Laxmikant Khanolkar
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Abstract
The present invention relates to the field of non-biodegradable stents, and therein to non-biodegradable stents coated with at least one layer of a biodegradable polymer which maintains mechanical integrity of the coating both in storage and upon balloon expansion and which can optionally release drugs. The at least one polymer layer comprises a biodegradable polymer and a plasticizer. The present invention also relates to a manufacturing method of such a non-biodegradable stent.
Claims21
-45. (canceled)
A non-biodegradable stent comprising a biodegradable coating wherein said coating comprises one or more polymer layers comprising a biodegradable polymer and a plasticizer, and wherein said coating comprises a drug combination of triflusal in an amount of about 1-15 wt % and sirolimus or a sirolimus derivative in an amount of about 1-15 wt %, based on dry weight of the respective drug containing layer.
Dependencies are inferred from the claim text.