Thoracic aorta and vagus nerve stimulation
AssigneeEnopace Biomedical Ltd.
InventorsYossi Gross, Amir Dagan, Yotam Reisner, Offer Glasberg, Nitai Hanani, Gal Ariav
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Abstract
Apparatus and methods are described including identifying a subject as suffering from a condition selected from the group consisting of congestive heart failure, diastolic heart failure, and hypertension. In response to the identifying, an electrode is placed on a vagus nerve of the subject at a vagal site that is between (a) a vagal bifurcation with a thoracic cardiac branch of the subject, and (b) thoracic vagal branching into the esophageal plexus of the subject. The subject is treated by driving a current into the vagal site, via the electrode. Other embodiments are also described.
Claims36
A method, comprising:
- identifying a subject as suffering from a condition selected from the group consisting of congestive heart failure, diastolic heart failure, and hypertension;
- and
- in response to the identifying:
- placing an electrode on a vagus nerve of the subject at a vagal site that is between (a) a vagal bifurcation with a thoracic cardiac branch of the subject, and (b) thoracic vagal branching into the esophageal plexus of the subject;
- and
- treating the subject by driving a current into the vagal site, via the electrode.
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A method, comprising:
- identifying a subject as suffering from a condition selected from the group consisting of congestive heart failure, diastolic heart failure, and hypertension;
- and
- in response to the identifying:
- placing an electrode on an aorta of the subject at an aortic site that is between first and fifth intercostal arteries of the subject;
- and
- treating the subject by driving a current into the aortic site, via the electrode.
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A method for use with one or more non-coronary blood vessels of a subject, and a body of a subject, comprising:
- at a first location in a vicinity of one of the blood vessels, detecting an electric signal that is indicative of electrical activity at the first location due to a cardiac cycle of the subject;
- and
- responsively thereto, generating an output at a location selected from the group consisting of:
- the first location, and a second location within the subject's body that is different from the first location.
28-29. (canceled)
37-46. (canceled)
Dependencies are inferred from the claim text.