Back to results
US 2010/0305328 A1Published application
Process for preparation of piperidine carboxylic acid
AssigneeRanbaxy Laboratories Limited
InventorsProsenjit BOSE, Pramod KUMAR, Shilpi MITTAL, Yatendra KUMAR
Life of this patent
Estimating the term…
Abstract
Processes for preparing pure tiagabine, a piperidine carboxylic acid, using pharmaceutically acceptable acid addition salts of tiagabine esters are provided. L(+)-tartaric acid, oxalic acid and dibenzoyl L(+)-tartaric acid addition salts of tiagabine esters are also provided. Further, processes for preparing acid addition salts of tiagabine esters are provided.
Claims10
An acid addition salt of tiagabine ester of Formula I,
- wherein R is L(+)-tartaric acid, oxalic acid or dibenzoyl L(+)-tartaric acid.
A process for preparing acid addition salts of tiagabine ester of Formula I,
- comprising contacting crude tiagabine ester with one or more acids in one or more inert solvents and isolating a corresponding acid addition salt of tiagabine ester.
Dependencies are inferred from the claim text.