Pharmaceutical Composition
AssigneeArmstrong Medical Limited
InventorDavid Nigel Armstrong
Life of this patent
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Abstract
A topical composition comprises at least 5-wt % metronidazole or a pharmacologically acceptable derivative thereof in a non-aqueous vehicle. The composition may be used in the treatment of conditions of the colon, rectum, anorectum and perianal region, in particular inflammatory bowel disease and perianal Crohn's disease. The composition also relieves pain and inflammation and promotes healing of the colon, rectum, and anorectum and perianal region following surgical operations. One advantage of the composition is that topical administration of metronidazole results in a primarily local effect and thus side effects observed from systemic administration are avoided.
Claims32
A method of relieving pain or promoting wound healing in a patient following a surgical operation to the colon, rectum, anorectum or perianal region of patient, said method comprising applying directly to the affected area a topical composition comprising metronidazole in a therapeutically effective concentration in a pharmacologically acceptable non-aqueous vehicle.
Dependencies are inferred from the claim text.