Novel Heterocyclic Derivatives
AssigneeOrchid Research Laboratories Limited
InventorsSurendrakumar Satyanarayan Pandey, Gadam Om Reddy, Shiv Kumar Agarwal, Gajendra Singh, Santhanagopalan Chithra, Debendranath Dey, Abhijeet Nag, Kadnur Venkatachalapathi Sanjay
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Abstract
The present invention relates to novel heterocyclic derivatives of formula (I) and their pharmaceutically acceptable salts, their derivatives, their analogs, their tautomeric forms, their stereoisomers, their polymorphs, their hydrates, their solvates, their pharmaceutically acceptable salts, their pharmaceutical compositions, and their prodrugs thereof. The present invention more particularly provides novel compounds of the general formula (1).
Claims12
Novel Heterocyclic derivatives of formula (I)
- their derivatives, their analogs, their tautomeric forms, their stereoisomers, their polymorphs, their hydrates, their solvates, their pharmaceutically acceptable salts, their pharmaceutical compositions, and their prodrugs thereof, wherein represents an optional bond;
- W represents O or S;
- X represents C, CH or N;
- Y represents NR5, S or O, wherein R5 represents hydrogen, substituted or unsubstituted alkyl, alkenyl, —CH2COOR, or aryl, or counter ion;
- wherein R represents H or alkyl group;
- Z represents CR6 or S;
- R1 represents ═O, ═S or together with R6 forms fused 5 or 6 membered aromatic or heteroaromatic ring system containing carbon atoms or 1 or 2 heteroatoms selected from O, S or N;
- R2, R3, may be same or different and independently represent hydrogen, halogen, hydroxy, nitro, cyano, formyl, amino, alkyl, haloakyl, alkoxy group;
- R4 may be same or different and independently represent H, COR7, substituted or unsubstituted groups selected from alkyl, alkenyl, aryl, aryloxy, alkoxy, heteroaryl or heterocyclyl;
- where R7 represents H, substituted or unsubstituted groups selected from alkyl, alkenyl, aryl, aryloxy, alkoxy or aralkoxy.
Dependencies are inferred from the claim text.