Administration of an Inhibitor of HDAC
AssigneeSyndax Pharmaceuticals, Inc.
InventorsKonrad Burk, Peter Ordentlich, Robert Goodenow
Life of this patent
Estimating the term…
Abstract
Methods of treating patients with SNDX-275 are provided.
Claims36
A method of treating cancer in a patient, comprising administering to the patient a first dose of 10 mg SNDX-275 during a first biweek of a biweekly dosing schedule and a second dose of 10 mg of SNDX-275 during a second biweek of the biweekly dosing cycle, wherein the biweekly dosing schedule comprises at least two consecutive biweeks.
-9. (canceled)
-15. (canceled)
A method of treating cancer in a patient, comprising administering to the patient at least one dose of 10 mg of SNDX-275 and at least one subsequent dose of 5 mg of SNDX-275.
-20. (canceled)
A method of treating cancer in a patient, comprising administering to the patient a first dose of 5 mg SNDX-275 during a first biweek of a biweekly dosing schedule and a second dose of 5 mg of SNDX-275 during a second biweek of the biweekly dosing cycle, wherein the biweekly dosing schedule comprises at least two consecutive biweeks.
-27. (canceled)
A method of treating cancer in a patient, comprising administering to the patient a first dose of 7 mg SNDX-275 during a first biweek of a biweekly dosing schedule and a second dose of 7 mg of SNDX-275 during a second biweek of the biweekly dosing cycle, wherein the biweekly dosing schedule comprises at least two consecutive biweeks.
-33. (canceled)
A method of treating cancer in a patient, comprising administering to the patient a first dose of 3 mg SNDX-275 during a first biweek of a biweekly dosing schedule and a second dose of 3 mg of SNDX-275 during a second biweek of the biweekly dosing cycle, wherein the biweekly dosing schedule comprises at least two consecutive biweeks.
-37. (canceled)
A method of treating cancer in patient, comprising administering a first dose of from 2 to 6 mg/m2 of SNDX-275 on a first day of an at least 28-day dosing, cycle, a second dose of from 2 to 6 mg/m2 of SNDX-275 on a second day of the at least 28-day dosing cycle and a third dose of from 2 to 6 mg/m2 on a third day of the at least 28-day dosing cycle.
-79. (canceled)
-86. (canceled)
A method of treating cancer in a patient, comprising administering to the patient a fixed dose of about 1 to about 10 mg of SNDX-275 one time every other week.
-96. (canceled)
Dependencies are inferred from the claim text.