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US 2010/0305089 A1Published application
Fused Bicycloheterocycle Substituted Azabicyclic Alkane Derivatives
AssigneeAbbott Laboratories
InventorsJianguo Ji, Tao Li, Christopher L. Lynch, Murali Gopalakrishnan
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Abstract
The invention relates to fused bicycloheterocycle substituted azabicyclic alkane derivatives, compositions comprising such compounds, and methods of treating conditions and disorders using such compounds and compositions.
Claims13
The compound of formula (I),
- or a pharmaceutically acceptable salt, ester, amide, or prodrug thereof, wherein
- n is 1, 2 or 3;
- A is N or N+-0−;
- R is hydrogen, alkyl, cycloalkylalkyl and arylalkyl;
- L is selected from the group consisting of O, S, and —N(Ra)—;
- Ar1 is a 6-membered aryl or 6-membered heteroaryl ring;
- and
- Ar2 is a bicyclic heteroaryl;
- and
- Ra is selected from the group consisting of hydrogen, alkyl and alkylcarbonyl;
- provided that if Ar1 is
- then L is O or S.
9 more elements
Dependencies are inferred from the claim text.