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US 2010/0305036 A1Published application
Combination of protein tyrosine phosphatase inhibitors and human growth hormone for the treatment of muscle atrophy and related disorders
OwnerDavid Barnes, Angelika Christina Paulinventors
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Abstract
The invention relates to the use of a combination of protein tyrosine phosphatase inhibitors and human growth hormone for the treatment of musculoskeletal diseases, particularly for the treatment of muscle atrophy.
Claims24
A method of treating a musculoskeletal disease, comprising
- identifying an individual exhibiting the musculoskeletal disease or at risk for developing the musculoskeletal disease;
- and
- administering to the individual a therapeutically effective amount of a PTP inhibitor in combination with human growth hormone sufficient to alleviate the musculoskeletal disease.
(canceled)
(canceled)
A method of increasing muscle or bone mass in an individual, the method comprising
- identifying an individual in which increasing muscle or bone mass is desirable;
- and
- administering to the individual an amount of a PTP inhibitor sufficient to increase the muscle or bone mass in the individual.
(canceled)
A pharmaceutical combination composition, comprising:
- a protein tyrosine phosphatase inhibitor compound,
- human growth hormone, and
- one or more pharmaceutical excipients.
Dependencies are inferred from the claim text.