Diagnostic Methods and Arrays for Use in the Same
OwnerCarl Arne Krister Borrebaeck, Lars Bertil Christer Wingreninventors
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Abstract
The present invention provides a method for determining the presence of breast cancer cells in an individual comprising the steps of (a) providing a serum or plasma sample to be tested and (b) determining a protein signature of the test sample by measuring the presence and/or amount in the test sample of two or more proteins selected from the group defined in Table 1a or 1b, wherein the presence and/or amount in the test sample of the two or more proteins selected from the group defined in Table 1a or 1b is indicative of the presence of breast cancer cells. In a preferred embodiment, the two or more proteins include IL-5 and/or MCP-3. Also provided are arrays and diagnostic kits for use in the methods of the invention.
Claims33
A method for determining the presence of breast cancer cells in an individual comprising the steps of:
- a) providing a serum or plasma sample to be tested;
- b) determining a protein signature of the test sample by measuring the presence and/or amount in the test sample of two or more proteins selected from the group defined in Table 1a or 1b, which two or more proteins include IL-5 and/or MCP-3;
- wherein the presence and/or amount in the test sample of the two or more proteins selected from the group defined in Table 1a or 1b is indicative of the presence of breast cancer cells.
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