Back to results
US 2010/0303906 A1Published application
Solid dosage forms of valsartan and amlodipine and method of making same
OwnerYatindra Joshi, Robert Frank Wagner +3inventors
InventorsYatindra Joshi, Robert Frank Wagner, Madhusudhan Pudipeddi, Gangadhar Sunkara, Ping Li
Life of this patent
Estimating the term…
Abstract
Monolayer and bilayer solid dosage forms of a combination of valsartan and amlodipine are made.
Claims21
A solid dosage form of valsartan comprising:
- valsartan;
- amlodipine;
- and
- pharmaceutically acceptable additives suitable for the preparation of solid dosage forms of valsartan.
1 more element
A method of making a solid dosage form of valsartan comprising the steps of
- (a) blending valsartan, amlodipine and pharmaceutically acceptable additives to form a blended material;
- (b) sieving the blended material to form a sieved material;
- (c) blending the sieved material to form a blended/sieved material;
- (d) compacting the blended/sieved material to form a compacted material;
- (e) milling the compacted material to form a milled material;
- (f) blending the milled material to form blended/milled material;
- and
- (g) compressing the blended/milled material to form a monolayer solid dosage form.
5 more elements
A method of making a solid dosage form of valsartan comprising the steps of:
- (a) granulating valsartan and pharmaceutically acceptable additives to form a valsartan granulation;
- (b) blending amlodipine and pharmaceutically acceptable additives to form an amlodipine blend;
- and
- (c) compressing the valsartan granulation and the amlodipine blend together to form a bilayer solid dosage form.
1 more element
Dependencies are inferred from the claim text.