Self-emulsifying pharmaceutical compositions of rhein or diacerein
AssigneeWockhardt Limited
InventorsPremchand Nakhat, Prashant Mandaogade, Girish Kumar Jain, Munish Talwar
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Abstract
The invention relates to self emulsifying drug delivery system based compositions of rhein or diacerein, or salts or esters or prodrugs thereof which are bioequivalent to a 50 mg diacerein formulation marketed under the trade name Art 50®. The compositions exhibit no variability in fed and fasted state conditions. The compositions also result in significant reduction in side effects such as, soft stools effects as compared to Art 50®. The invention also relates to methods for preparing such compositions.
Claims20
1-29. (canceled)
A pharmaceutical composition comprising a self-emulsifying drug delivery system of rhein or diacerein, or salts or esters or prodrugs thereof in one or more pharmaceutically acceptable vehicles.
A pharmaceutical composition comprising supersaturable self-emulsifying drug delivery system of rhein or diacerein, or salts or esters, or prodrugs thereof in one or more pharmaceutically acceptable vehicles, optionally with one or more pharmaceutically acceptable excipients.
Dependencies are inferred from the claim text.